Neuropathic Pain

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Neuropathic pain is a type of chronic pain that is caused by damage or dysfunction of the nervous system. This pain is often described as a burning, stabbing, or shooting sensation and can be difficult to manage with traditional pain medications. Understanding the mechanisms, symptoms, and diagnosis of neuropathic pain is important for healthcare professionals and patients alike.

What Causes Neuropathic Pain?

Neuropathic pain can occur as a result of damage to any part of the nervous system, including the peripheral nerves, spinal cord, or brain. This damage can be caused by a variety of factors, including injury, infection, surgery, or certain medical conditions such as diabetes or multiple sclerosis. It is also common in patients with HIV, and often affects people undergoing cancer treatments.

When the nervous system is damaged, it can become hypersensitive, leading to abnormal signals being sent to the brain. These abnormal signals can cause the sensation of pain, even in the absence of an actual injury. In addition, the nervous system may also undergo structural changes, which can further contribute to the development and persistence of neuropathic pain.

What are the Symptoms of Neuropathic Pain?

The symptoms of neuropathic pain can vary depending on the underlying cause and location of the nerve damage. Common symptoms include:

  • Burning, shooting, or stabbing pain
  • Tingling or numbness
  • Increased sensitivity to touch or temperature changes
  • Muscle weakness or twitching
  • Loss of coordination or balance

Neuropathic pain can also be associated with other symptoms, such as depression, anxiety, and sleep disturbances. It is important to note that not all individuals with neuropathic pain will experience the same symptoms, and some may have only mild or intermittent pain.

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How is Neuropathic Pain Diagnosed?

Diagnosing neuropathic pain can be challenging, as there is no single test that can definitively confirm its presence. Healthcare professionals may rely on a combination of patient history, physical examination, and diagnostic tests to make a diagnosis.

During a physical examination, healthcare professionals may look for signs of nerve damage, such as muscle weakness or loss of reflexes. They may also test the patient’s response to various stimuli, such as touch or temperature changes, to assess for abnormal sensations.

Diagnostic tests, such as nerve conduction studies or electromyography, may also be used to evaluate nerve function and identify areas of nerve damage. Imaging studies, such as MRI or CT scans, may be ordered to assess for structural abnormalities or other potential causes of neuropathic pain.

Once a diagnosis of neuropathic pain has been made, healthcare professionals will work with patients to develop a treatment plan. This will usually involve a combination of medications, such as amitriptyline, gabapentin or duloxetine. However, for many people, these are often ineffective and come with serious side-effects.

A robust body of evidence has found repetitive transcranial magnetic stimulation (rTMS) to be effective for the treatment of neuropathic pain. This non-invasive, safe, medication-free and painless alternative looks set to revolutionise the management of this debilitating condition, and we are proud to be at the forefront of this movement. To read about how rTMS works to relieve neuropathic pain, click here.

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